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To restore vascular tone using a vasoconstrictor. Of the entire group has the greatest stimulant caffeine, which is a toxic dose at 1 g, and smertellnaya dose - about 20 grams with large individual differences. If the poisoning is caused by candles containing aminophylline, put an enema, take saline laxative metarule . Symptoms. Increased motility or dramatically inhibited perestaltika gastrointestinal tract, combined with a decrease in saliva secretion and sensation of dry mouth. Used emetics, artificial respiration at occurrence of respiratory failure. Heart failure is also possible when rapid introduction of non-aminophylline. All are easily absorbed in the gastrointestinal tract and form strong connections with blood proteins and tissues. Protnpodepresspvnye drugs. Characterized by changes in the central and the cardiovascular system. The main drug, giving the antidote effect is physostigmine, which is injected intravenously. For the prevention of pneumonia Antibiotics, with a sharp increase in temperature - Magnesium Sulfate 10 ml 4% solution amidopirina. To relieve spasms and psychomotor agitation appropriate use of barbiturates and chlorpromazine. The most dangerous complication of caffeine and its analogs Telephone Order development of acute cardiovascular disease with symptoms of collapse. In marked violation of respiration is carried out intubation, suctioning the contents of the bronchi and ventilation, with minor respiratory distress resorted to respiratory stimulants (analeptics). When intravenous aminophylline, there are cases Death on the dose of the order of 0,1 g, lethal doses in children when administered in the candlelight - 25100 mg / kg. Main manifestation of toxic effects on the myocardium are expressed for the first 12 hours, but may develop in the next 6 days. With the cardiovascular system - tachycardia, a tendency to collapse, respiratory failure, cyanosis. Already early after poisoning occurs psychomotor agitation, hallucinations occur, metarule temperature drops sharply the body develops a coma with respiratory depression. The severity of poisoning shows a sharp pupil dilation, dryness oral mucosa, dysmotility of the gastrointestinal tract until enteroparesis. Contraindicated in heart glycosides, as toxicity of tricyclic antidepressants in this increases sharply.