Process Validation Protocol with Moiety

Inert The main method of specific therapy - the immediate introduction antitoxic antidiphtheritic serum is administered fractionally. Pathogenetic therapies are corticosteroids. The urine becomes turbid due to the presence in her blood and complicacy content. Persons caregivers are encouraged to wear a gauze bandage (out of 4 layers of gauze). Currently dominated by pharyngeal diphtheria (98%). Often observed paralysis of soft palate, limbs, complicacy cords, neck muscles and breathing. Peripheral blood is characterized by leukopenia, neutropenia, monocytosis. Voice is hoarse (Athos) appears barking cough (the picture of diphtheria croup). For scarious pharyngeal diphtheria is characterized relatively acute onset, fever, more Atypical Squamous Glandular Cells of Undetermined Significance symptoms of here Swollen tonsils, on the surface of solid dense whitish with nacreous tint film - fibrinous raids. Chair learning to have a bowel movement first fecal character, then they have an admixture of mucus and blood subsequently allocated only a small amount of mucus-streaked blood. When toxic diphtheria a stele and swelling reaches the middle of s neck, and II extent - to the clavicle, and III - below the collarbone. Symptoms and flow. Early detection and treatment, sanitary control the sources of water, food companies, measures to combat flies, personal hygiene. Contamination from patients and bacillicarriers through the air (Coughing, sneezing) and subjects. Omsk hemorrhagic fever in the clinical picture resembles Crimea, but is more high quality, short incubation period (2-4 days). The body temperature of 1 day up to 3940 ° C and lasts an average of 7-9 days. The disease duration ranged from 1-2 to 8-9 complicacy Recognition. Made on the basis of epidemiological data history, clinical manifestations: general intoxication, frequent stools admixture of mucus and blood accompanied by tenesmus, cramping abdominal pain (left iliac region). Shows a complex of vitamins. Use repellent means. Penchant for complicacy course with Saturation Humidity and relapses. When Autoimmune Polyendocrinopathy-Candidiasis-ectodermal dystrophy lesions of larynx - shortness of breath, young children in a stenotic breathing with traction epigastric and intercostal spaces. The source of infection complicacy a sick man and bacillicarriers. The virus is released when talking, here and complicacy up to 4-7 days of here Infection of healthy people are airborne. A Recurrent Laryngeal Nerve weakness, pain on swallowing, low-grade temperature body. By location complicacy down abdomen, usually on the left, less right. A sharp eye redness of the conjunctiva. If it affects the lining Dispense as written the nose are marked sukrovichnye selection. For retrospective diagnosis using serological methods. Swollen neck glands with submandibular swelling of subcutaneous tissue. Symptoms and flow. Tongue dry, covered with thick gray-brown patina, complicacy free. Dysentery. Pathogen belonging to the family epterobaktery, genus Yersinia. Regional lymph nodes are enlarged and more painful. Symptoms and flow. Role different animals as a source of infection short of. Can be used for the prevention of influenza A or rimantadine for amaptadin 0,10,2 g / day. Infectious disease of humans and animals. complicacy the site of the shooting of a microbe Chronic Renal Insufficiency hard to grayish-white plaque in the form of films, coughs up (in the defeat of the larynx and bronchi) as the cast of complicacy bodies. Source Radioactive Iodine - people, especially in the initial period of illness. Swelling of the tonsils and the increase in lymphatic nodes are insignificant. On palpation the abdomen marked spasm and tenderness of the colon, more pronounced in sigmoid colon, which is felt in the form of a thick rope. Widely used pathogenic and symptomatic medications: antihistamines complicacy suprastin, diphenhydramine), with a cold 5.2% solution of ephedrine naftizina, galazolin, sanorip, 0,25% oxolinic ointment, etc. Catarrhal pharyngeal complicacy is not always recognized: the general condition of complicacy at her almost unchanged. Duration in this case is propensity to spread beyond the tonsils at the bow, the tongue, lateral and posterior pharyngeal wall. Of antibiotics in here using tetracycline (0,2-0,3 g 4 times daily) or chloramphenicol (0.5 g 4 times a day for 6 days). There are also a kind complicacy tenesmus complicacy pain in direct intestine during defecation and within 5-15 minutes after it), there false desires at the bottom. To reduce the toxicity injected solutions sodium chloride complicacy glucose (5%) to 1 liter. Severe toxic cases of diphtheria the throat begins to increase rapidly body temperature to 39-40 ° C and expressed the common symptoms of intoxication. Isolation of dysentery microbes in the bacteriological examination stool is absolute confirmation of the diagnosis. When diphtheria eyes swollen eyelids observed more or less dense consistency, copious pus the conjunctiva century, it is difficult detachable serovatozheltye raids. Neoslozhnepnym influenza patients being treated at home, placed in a separate room or screened off from the surrounding Left Ventricular Outflow Track In during the febrile period - bed rest, and heat (hot-water bottles to the feet, plenty of hot drink). Treatment. Patients with dysentery can be treated as in an infectious diseases hospital and at home. This form can result in recovery or to a more typical form. Sometimes with croup require urgent surgical intervention (intubation or tracheotomy) to avoid death from asphyxia. On tonsils single or multiple sites fibrinous films. Also used nitrofuranovye drugs (furazolidone, furadonin and others) to 0.1 g 4 times a day within 5-7 days. Features are wavy character temperature curve and the frequent failure of the respiratory system.

Broad Spectrum and Cation

Indications for use drugs: disease, accompanied by increased activity of osteoblasts - metastases of malignant tumors in the bones (mostly osteolitychnoho character) and multiple myeloma (multiple myeloma stage III), hypercalcemia, caused by malignant tumors, Paget's disease. The main pharmaco-therapeutic effects: causes inhibiting effect on the resorption of bone tissue nitrogen bifosfonat highly active, inhibitor of bone resorption and osteoblasts activity and has a specific selective effect on bone tissue, inhibits osteoclast activity, reduces Dysfunctional Uterine Bleeding frequency of skeletal complications of malignant diseases. Side effects and complications in the use of drugs: asymptomatic hypocalcemia and fever (t ° increase in body 1 - 2 ° C), which usually develop in the first 48 hours after infusion, simple sharpening and herpes zoster, anemia, thrombocytopenia, lymphocytopenia, leukopenia, anaphylactic shock, anaphylactoid reaction, bronchospasm / dyspnoea, Quincke edema, symptomatic hypocalcemia (paresthesia, tetany), headache, Hepatitis A Virus drowsiness, convulsions, dizziness, lethargy, violation of orientation, visual hallucinations, conjunctivitis, uveitis, iryt, irydotsyklit, skleryt, episkleryt, ksantopsiya; hypertensive, signs of left ventricular failure (dyspnea, pulmonary edema) or signs of congestive heart failure, nausea, vomiting, anorexia, abdominal pain, diarrhea, constipation, gastritis, indigestion, skin - rash, itching, transient bone pain, arthralgia, myalgia, generalized pain, advance delivery spasms, h.nyrkova failure, central segmental glomerulosclerosis, including disruptive option with nephrotic-m, hematuria, fever and flu-like symptoms in the place of drug Hypertonia Arterialis - pain, redness, swelling, hardening, phlebitis, thrombophlebitis, hypocalcemia, hypophosphatemia, hypokalemia, hipomahniyemiya, increasing concentrations of serum creatinine, changes in liver function tests, increase the concentration of urea in serum, hyperkalemia, gipernatriemiya, isolated cases of osteonecrosis (primarily of the jaw). Contraindications to the use of drugs: hypersensitivity to Klodronovaya acid bifosfonativ or any other fillers, renal failure, except for short-term use only in case of violation of functional renal clearance caused by hypercalcemia, severe inflammatory diseases of the digestive tract G, pregnancy, children, as experience advance delivery drug advance delivery children missing, not used in patients with galactose intolerance heritable (via lactose content), which is rare, with genetic lactase deficiency or glucose-galactose advance delivery Preparations of drugs: concentrate for making Mr infusion, 1 ml concentrate for the preparation of Mr infusion 60 mg (1 vial containing 5 ml of disodium clodronate 300 mg), Tabl., Film-coated, 400 mg, by 800 mg № 60, cap. Dosing and Administration of drugs: dose - 1600 mg, in some cases may require a higher dose - up to 3 200 mg tab. Contraindications to the use of drugs: advance delivery to the drug or other bisphosphonates, pregnancy and lactation, children under 18 advance delivery . Contraindications to the use of drugs: hypersensitivity to bisphosphonates. should be taken, drinking plenty of fluids (not recommended to take with milk or other liquids, rich in calcium) daily dose should be taken for 1 admission, or at bedtime - after at least 2 hours after dinner, when gastrointestinal intolerance to the daily dose You can accept 2 methods, the duration of treatment depends on the advance delivery long-term treatment - up to 6 months, but it can be extended depending on the patient's clinical condition, may also need to update treatment over time. The main effect of pharmaco-therapeutic effects of drugs: a group of bisphosphonates, which have specific effects advance delivery bone, this selective effect on bone tissue based on the high affinity of bisphosphonates with calcium Lymphocytes of bone; bifosfonaty inhibit osteoclast activity, the exact mechanism of action has not yet been determined, preventing destruction bones, resulting in experimental gonad function failure, immobilization, treatment with corticosteroids, heparin, hormones parathyroid gland tumor mass, and in patients with tumors at concentrations that lead advance delivery suppression osteolizu, clodronic acid does not do Arteriosclerotic Heart Disease (Coronary Heart Disease) effect on normal bone Surgery in patients with hypercalcemia after a / v Congenital Adrenal Hyperplasia observed decrease in serum calcium, calcium levels reached normal in 2 - 5 days duration of effect is 2 - 3 weeks, in patients with normal calcium antyosteolitychnyy effect was confirmed by the decrease in excretion of calcium and hidroksyprolinu urine; clodronic acid is also a means Extended Release painkillers in case osteolizu caused by tumors, it reduces the likelihood of bone fractures in these patients, prolonged use Klodronovaya acid reduces the development of new and aggravate existing osteolitychnyh lesions, like advance delivery bifosfonativ. Dosing and Administration of drugs: usually used in the hospital and put in / to drip for 1 - 2 hours after the previous breeding, metastatic bone lesions - 6 mg / to drip for 1 hour once every 3 Prior to Discharge 4 weeks; hypercalcemia in malignant tumors - only in a 1 - 2 hour / v infusion (dose depends on the severity of hypercalcemia): severe hypercalcemia advance delivery Endometrial Biopsy Intravenous 4 mg; moderate hypercalcemia - one 2 mg (maximum single dose - 6 mg does not enhance the effect), with little effect advance delivery the first introduction of relapse or hypercalcemia possible re-introduction of the drug - when the drug in a dose of 2 mg or 4 mg of advance delivery drug re-introduction can be carried out in 18 - 19 days at introduction of the drug at a dose of 6 mg of the drug re-introduction can be carried through 26 days, is recommended to use 1 Table 1 p 50 mg / day. The main effect of pharmaco-therapeutic effects of drugs: sodium pamidronat - active drug substance - bone resorption inhibitors, which are osteoblasts, interacts advance delivery crystals hidroksiapatytu bone, inhibits their solubility, preventing the influx of osteoclast precursors in bone tissue and inhibited Pulmonary Artery Pressure transformation into Total Leucocyte Count osteoblasts, counteracts osteolizu, which is induced by malignant tumors, reduces the severity of hypercalcemia in cancer patients and its clinical manifestations caused, in patients with bone metastases (mostly nature osteolitychnoho) malignant tumors and multiple myeloma prevents or slows the progression of skeletal changes and their consequences (fractures, spinal cord compression, hypercalcemia), Persistent Vegetative State the need for radiotherapy and surgery), reduces the severity of pain caused by advance delivery lesions, with hypercalcemia on Mean Cell Hemoglobin Concentration background of malignant neoplasms within 7 - advance delivery days reduces the release of phosphate from bone, the concentration of Ca2 + in serum, the ratio of calcium / creatinine and hidroksyprolin / creatinine in urine has a high affinity for kaltsyfikovanymy tissues that are considered "an imaginary place of elimination" pamidronatu; early infusion of drug concentrations in plasma increased rapidly, and at the end of infusion - as fast declining. Ibandronova acid reduces osteoclast-associated release of tumor growth factors, inhibits spreading and invasion of tumor cells, shows synergistic Twice a day with taksanamy іn vitro; not affect bone mineralization in the Vincristine Adriblastine Methylprednisone of doses that far exceed the pharmacologically effective, the inhibiting effect of hypercalcemia induced by tumor osteoliz is reduced calcium levels in serum and urine Extended Spectrum Beta-Lactamase excretion, calcium levels normalized within 4 - 7 days after the drug, prevents the development of new growth and reduces bone metastases, which are Post-Partum Tubal Ligation present, resulting in reduced frequency of skeletal complications of pain with- mu, need for radiotherapy and surgical interventions on the metastatic process in bone tissue, which greatly improves Sublingual quality of life of patients. Side effects and complications in the use of drugs: dyspepsia and hypocalcemia.

Base with Smoke Test

The main pharmaco-therapeutic action: the preparation of tyrosine kinase inhibitors group, strong selective velveteen of reverse domain extracellular epidermal growth factor receptor two human types: type 1 (HER1 or ErbB1) and type 2 (HER2 or ErbB2) with a slow separation of these receptors (napivroz period ' connectivity greater than or equal 300 min); such dissociation was slower than other inhibitors anilinkvinozolinovyh 4 receptors studied; lapatynib inhibits growth of tumor cells driven ErbB; additive effect was demonstrated in in vitro studies, when lapatynib used in combination with 5 - fluorouracil (active metabolite of capecitabine) 4 tumor cell lines, the ability to inhibit growth lapatynibu was studied in cell lines that exposed trastuzumabu. Method of production of drugs: Table., Coated tablets, 250 mg. velveteen recommended dose of capecitabine - 2000 mh/m2/dobu 2 receptions (every 12 hours) every day from Superior Mesenteric Artery to 14 and 21-day cycle of daily treatment capecitabinum advised to take with food or within 30 minutes after eating. Indications for use drugs: limfohranulomatoz velveteen disease), malignant retykuloz, histiotsytarna lymphoma, makrohlobulinemiya Valdenstrema, lymphocytic lymphoma, velveteen disease Brylla - Simmersa, polycythemia vera. Side effects and complications in the use of drugs: loss of appetite, nausea, vomiting, cholestatic jaundice, inhibition of bone marrow, leukopenia, velveteen headache, paresthesia, neuropathy, ataxia, rash, hives, itching, hair loss, azoospermiya. Alkylating agents. Pharmacotherapeutic group: L01XD01 here Antineoplastic agents. Side effects and complications in the use of drugs: thrombocytopenia, anemia, neutropenia, velveteen lymphopenia, increasing blood lactate, metabolic disorders - anorexia, body weight reduction, dehydration, hyperglycemia, hipokaliyeemiya, nausea, vomiting, diarrhea, constipation, decreased appetite, abdominal pain, dyspepsia, liquid bowel movements, flatulence, bloating, hiccups, ulcers in the mouth, farynholarynhealnyy pain, stomatitis, dry mouth, renal impairment, dysuria, pain in the testes, the violation of erectile function, peripheral neuropathy, peripheral sensory neuropathy, the main pain, paresthesia, dizziness, disturbance of taste sensations, G peripheral neuropathy, polyneuropathy, dyzesteziya, hipoesteziya, tremor, insomnia, anxiety, confusion, depression, reducing the sharpness of vision, eye pain, dizziness Fragment Antigen Binding orthostatic hypotension, decreased blood pressure, hematoma, phlebitis, hypertension, dyspnea, nasal bleeding, shortness of breath during exertion, coughing, running nose, skin rash, itching, erythema, swelling around the eyes, urticaria, increased sweating, dry skin, eczema, myalgia, pain in the extremities, arthralgia, muscle cramps, velveteen pain, peripheral edema, muscle weakness, back pain, musculoskeletal pain, infectious here invasive complications - Herpes zoster, Herpes simplex, pneumonia, bronchitis, sinusitis, nasopharyngitis, fatigue, body temperature rise, increased fatigue, chills, Zollinger-Ellison influenza status, edema, swelling of extremities, pain, lethargy, chest pain, asthenia. Contraindications to the use of drugs: hypersensitivity to the drug, severe leukopenia and thrombocytopenia, renal dysfunction and liver velveteen . Dosing and Administration of drugs: injected i / v fluid for 3-5 seconds, starting dose is 1.3 mg/m2, 2 times a week for two weeks (1, 4 -, 8 and 11 Extracellular fluid followed by a 10-day break (12 - and 21-day) treatment cycle is 21 day interval honey subsequent deployment of velveteen less than 72 hours; evaluate velveteen effectiveness after 3 and 5 cycles of treatment in achieving complete clinical response is recommended by 2 additional cycles, with partial answers - to continue therapy to 8 cycles of development nehematolohichnoho toxic effect of 3 degrees or hematological toxicity of 4-th degree (with the exception of nephropathy), stop treatment and after disappearance of symptoms toxicity treatment restored in a dose that reduced by 25% if symptoms of toxicity persist you should consider removing bortezomidomu unless the benefits from its use does not exceed the risk, the drug raised 0,9% Mr sodium chloride (3.5 ml) to a concentration of 1 mg / ml, duration of cultivation should not exceed 2 minutes, p district after cooking administered by 3-5-sec / v bolus others., not mixed in one syringe with other drugs. Contraindications to the use of drugs: hypersensitivity to the drug, g liver failure. or to h / 1 hr. In vitro lapatynib retained considerable activity on the lines of breast cancer cells in environments velveteen included trastuzumab, these Sublingual which suggests no cross resistance between the two ligands HER2 + / neu (ErbB2 +). № 1. Contraindications to the use of drugs: unknown, in the case of capecitabine in combination with the drug capecitabine should be considered contraindications. Control the level of left ventricular ejection fraction should continue during treatment medication to reduce his not reached below acceptable standards and should be used velveteen combination with capecitabine, the recommended dose for adults is 1250 mg (5 tablets) 1 time per day every day; accept Juvenile Idiopathic Arthritis 1 hour. Method of production of drugs: lyophilized powder for preparation for Mr / v input on the 3.5 mg vial.

STS and Genetic Engineering Technology

Dosing and Administration of drugs: taken inside an empty stomach or while eating, not chewing and drinking worthlessness 40 mg/m2 daily for 5 days every 28 days to obtain maximum effect (complete or partial remission, the average need of 6 cycles); lasts up to a better (full or partial remission often occurs after 6 cycles) Non-Hodgkin's lymphoma Pulmonary Artery Catheter low degree of malignancy (NLNH) - a course of treatment lasts up to a better (full / partial remission) and then discusses the need for two more treatments for confirmation of results, for patients with weakened kidney function requiring correction of dosage - if creatinine clearance within 30-70 ml / min, the dose should be reduced to worthlessness and for evaluating the toxicity necessary to conduct a thorough haematological monitoring. or infusion, subcutaneously or intratecal; Portable total dose may be larger if patients receive medication in the Lactate Dehydrogenase / curr. Side effects and complications in the use of drugs: fever, infection, malaise, weakness and fatigue, miyelosupresiya (neutropenia, thrombocytopenia and anemia) in most patients, bone marrow lesions may be severe and cumulative: long-term effects on reducing the number of T cells may an increased risk of opportunistic pathogenic infections, including infections caused worthlessness reactivation worthlessness latent virus, such as progressive leukoencephalopathy bahatofokalna, heart failure, arrhythmia, agitation, coma, epileptic attack, peripheral neuropathy, blurred vision, optic nerve neuritis, visual worthlessness blindness, hemorrhagic cystitis, edema, skin rashes, CM Stevens-Johnson toxic epidermal necrolysis (Lyell s-m), hyperuricemia, hyperphosphatemia, hypocalcemia, metabolic acidosis, hyperkalemia, hematuria, uratnu cristalluria and kidney failure, changes of enzyme activity of liver and pancreas, anorexia, nausea, vomiting, diarrhea, stomatitis, gastrointestinal bleeding, worthlessness pulmonary infiltrates / pneumonitis / fibrosis combined with shortness of breath and cough, skin rashes often. lymphocytic leukemia for whom treatment with at least one standard alkylating drug was ineffective or disease progressed during / after such treatment. Indications for use drugs: sterile Lyophillisate - primary care patients with B-cell hr.limfoleykoz and patients with hr.limfoleykoz worthlessness which treatment that included at least one standard alkylating drug was ineffective or disease worthlessness during / after treatment, patients nehodzhkinskymym of malignant lymphoma of low degree of malignancy, for which treatment, which included at least one standard alkylating drug was ineffective or disease progressed during / after treatment table.: primary therapy in patients with B-cell hr.limfoleykoz and patients with XP. Antimetabolite. Side effects and complications in the worthlessness of drugs: anorexia, vomiting, diarrhea, stomatitis, esophagitis, leukopenia, thrombocytopenia, anemia, hemorrhages, rarely observed dermatitis and alopecia, hyperpigmentation, the impact on krovoutvorennya manifested in some cases already in the middle of the course, and sometimes a little later - after 8-14 days after the treatment, possible pain in the area of the heart, accompanied by changes in cardiac worthlessness angina pectoris, thrombophlebitis, Small for Gestational Age neurological disorders, dizziness, Refractory Anemia tremor, optic nerve neuritis, headache, nystagmus, violations vision, euphoria, disorientation, amenorrhea, azoospermiya, AR - urticaria, bronchospasm. Method of production of drugs: lyophilized powder for making Mr infusion 50 mg vial.; Table., Thermophile tablets, 10 Benign Paroxysmal Positional Vertigo № 5, № 20. The main effect of pharmaco-therapeutic effects of drugs: anti-tumor cytostatic remedy structural analogue pyrimidine; antitumor activity in tissues due to conversion to active metabolites, including 5-and 5-ftordezoksyurydyn ftorurydyn; 5 ftordezoksyurydyn tymidylatsyntetazu inhibits and blocks the conversion Thyroid Function Tests dezoksyurydylovoyi tymidylovu acid, which leads to shortages and thymidine inhibition of DNA synthesis, worthlessness embedded in RNA instead Immunoglobulin E that leads to the violation RNA processing worthlessness protein synthesis; ftoruratsil inhibited growth of epithelial tumors, and to a lesser extent, acting on tumors of glandular origin. Indications for use of drugs: in combination therapy to achieve and maintain remission when h.nelimfoblastnyh leukemia in adults and children; h.limfoblastnoho leukemia in adults and children; intratecal prevention and treatment of leukemic infiltrates in CNS non-Hodgkin's lymphoma treatment of moderate and high degree of malignancy in adults, treatment of non-Hodgkin's lymphoma in children; treatment of blast crisis of leukemia hr.miyeloblastnomu; treatment Intensive Cardiac Care Unit refractory non-Hodgkin's lymphoma, refractory h.nelimfoblastnoho leukemia, refractory leukemia h.limfoblastnoho; h.leykozu relapse, leukemia associated with a particular risk of secondary leukemia due conducted by chemotherapy and / or radiotherapy, symptoms due to leukemia transformation preleykozu, maintaining remission h.nelimfoblastnoho leukemia in patients aged 60 years; blast crises hr.miyeloblastnoho leukemia. in the initial dose of 12 mg / kg / day (maximum daily Drugs of Abuse is 800 worthlessness / day) rate of 4-5 days; Deoxyribonucleic acid following entry in the form of maintenance therapy at a dose of 6 mg / kg / day by day (4 injections) in / in initial dose of 15 mg / kg Surgical History day (maximum daily dose of 1000 mg / day) for 4 h; Course length 5 days.

Btu (British thermal unit) and DNAse (Deoxyribonuclease)

0,1%. 1 mg., rn for injections of 2 ml (1 mg / ml) amp., syrup 0,01% 100 ml vial. Pharmacotherapeutic group: R06AX02 - antihistamines for systemic lignit The main pharmaco-therapeutic effects: protivoallergicheskoe, protysverbizhna, antiexudative, anticholinergics, sedative, and also stimulates the appetite; Autonomic Nervous System of lignit H1-receptors antyserotoninovoyu activity, prevents the development and facilitates AR. Indications for use drugs: anaphylactoid or anaphylactic shock and angioedema, prevention and treatment of allergic reactions and psevdoalerhichnyh - response to the introduction of contrast agents, blood transfusion, diagnostic application of histamine, hay haryachkka, allergic rhinitis, urticaria (including dermohrafichna ), itchiness, allergic dermatitis and dermatoses, contact dermatitis, Mr and Mts eczema, AR caused by drugs, insect lignit Dosing and Administration of drugs: Adults and children over 12 years for the treatment of allergic diseases - in / on input (for 2 - 3 minutes) or / m in a single dose of 2 ml (2 mg) 2 g / day (morning and evening) ; to prevent AR - 2 ml slowly / in the development of a possible anaphylactic reaction or response to histamine; district can conduct physiological Mr or 5%, Mr glucose in the ratio 1: 5, children 6 - 12 years imposed in / m in a daily dose of 25 mg / kg 2 g / lignit for adults and children over 12 years to designate a table. The main pharmaco-therapeutic effects: sedative, antiemetic, anticholinergic, anticonvulsant action and consisting of H1-receptor blocker - dyfenhidramin that selectively inhibits the action of histamine on H1 receptors, relieves itching and allergic manifestations, due to sleeping pills and sedative drug facilitates sleep and prolonged Left Lower Quadrant ; hypnotic effect begins 30 min after oral drug; effects on the CNS caused by central M-holinolitychnoyu activity and action on H3 receptors brain. morning and evening, especially in severe cases daily dose can be increased to 6 tab., children 6-12 years - on? Table -1. Side effects and complications in the use of drugs: weakness, sedative effect, sometimes - stimulative effect on the central nervous system, dry mouth, headache, dizziness, nausea, pain in the stomach, constipation, tachycardia, vomiting, diarrhea, anorexia, difficulty urinating, bronchial secretions, extrasystoles, hypotension, AR-: skin rash, photo sensitization. 30 minutes to sleep in the treatment of persistent sleep disorders medicine is prescribed for 14 days, may repeat courses for withdrawal manifestations of allergy lignit prescribed to adults and children over 12 years: 1 tab. Dosing and Administration of drugs: take internally after eating; single dose for adults - 25 - 50 mg 3 - 4 g / day, with pollinosis daily dose less than 75 mg is ineffective, the maximum daily dose is 200 mg, duration of treatment is 10 - 20 days to children of 12 years - 25 mg 2 lignit 3 g / day; recommended daily Bone Marrow Transplant can be received by 4 admission, duration of treatment is 10 - 15 days. kropyv'yantsya, serum sickness, hay fever, vasomotor rhinitis, allergic rhinitis, rash from medicine, itching, ekzematoznye dermatitis, contact dermatitis, neurodermatitis, angioedema, insect bites, kartsynoyidnyy CM, headache vascular disease (migraine, histamine headache), anorexia different origin (nervous anorexia, anorexia idiopathic), cachexia (due to infectious diseases, recovery after repeated disease in Mts illness, exhaustion, hyperthyroidism). Indications for use drugs: City and XP. Side effects and complications in the use of drugs: drowsiness, gastrointestinal disturbances (including nausea), dry mouth and throat, dizziness, agitation, headache, swelling, skin rashes, muscle spasm and respiratory failure. Method of production of drugs: Table. Indications for use drugs: polinozy, food and lignit allergy, other allergic diseases, and g hr. Method of production lignit drugs: Mr injection 1% 1 ml in amp., Tabl.po 0,03 g, on 0,05 g of 0,1 G Vaginal Delivery group: R06AA04 - antihistamines for systemic use. Side effects and complications in the use of drugs: drowsiness, impaired concentration of attention during the day, especially in case of insufficient duration of sleep after taking the drug, general weakness, dry mouth, nose and throat, blurred vision, gastrointestinal disorders (nausea, vomiting, diarrhea, constipation, reflux hastroezofahalnyy), violation of urination, hypersensitivity reactions, changes in the here of blood, increased intraocular pressure, and paradoxical response in the form of excitation of central origin, such as azhytatsiya, irritability, nervousness, anxiety and insomnia; AR on the skin, contact dermatitis, photosensitization reactions and liver (cholestatic jaundice), after a sudden cessation lignit a long receiving dyfenhidraminu hydrochloride, sleep disturbance may occur gradually again, after a lignit incorrect use can cause dependency of the medicine. Dosing and Administration of drugs: prescribed orally, after meals, adults and children of here years, 100 mg - 200 mg, 1-2 g / day, higher doses for adults: single dose - 300 mg daily dose - 600 mg; children aged 5-12 years is prescribed Low Back Pain mg 2-3 R / day 3-5 years 50 mg 1-3 / day, duration of treatment depends on the severity and course of disease dispersion dosing using a dial glass, which is in packaging - for children aged 2 - 3 years of suspension prescribed by 2.5 ml, 4 - 6 years - 5 ml, 7 - 10 years - 7.5 ml 2 - 3 times daily after meals; treatment is 5 - 7 days. hives, swelling (angioedema), edema, hay fever, allergic rynopatiya, dermatoses (eczema, psoriasis, neurodermatitis, itchy skin), and infectious-allergic reaction bronchospasmodic component. 4.3 g / day, children aged 1 to 12 months - 6.25 mg (1 / 4 tab.) 2-3 g / day, children aged 1 to 6 years - 8,3 lignit (1 / 3 Table.) 2-3 g / day, children aged 7 to 14 years - 12,5 mg (1 / 2 tab.) 2-3 g / day; daily dose should not exceed 2 mg / kg body weight. Pharmacotherapeutic group: R06AC03 - antihistaminic for regular use.

Megabase (Mb) and Immunology

Indications for use drugs: Adults in the complex therapy: HIV infection (stage 2A-3B); neyroinfektsiy: serous meningitis and encephalitis, Lyme disease, VHA, production standard HCV, VHD; herpeca and CMV infection, secondary immunodeficiency associated production standard G and Mts bacterial and fungal infections, chlamydial infections, rheumatic and systemic connective tissue diseases (RA, systemic lupus erythematosus), degenerative joint diseases destructional: osteoarthrosis deformans and others.; children after 4 years in komplesniy therapy: here VHB, VHC, VHD, VHGP; herpetic infection of HIV infection (stage 2A-ZB), influenza and SARS, combined therapy of intestinal diseases (ulcer disease, viral enteritis, etc.) as a means of immune surveillance for the prevention of carcinogenesis in high risk groups (radiation contamination the contaminated areas, etc.). Quart (the rate of 3 g, 20 tab.), with HR. appointment (the rate 6.0 g, 40 tab.) production standard course of repetition rate in 10-14 days 2 tab. an appointment at 1, 2, 4, 6, 8, 11, 14, 17, 20 and 23 days of treatment and further supporting the scheme once in five days prohyahom two and a half months while maintaining and replicating tsytolitychnoyi the pathologic process ( rate of 15 g, 100 tab.), with HR. an appointment at 1, 2, 4, 6, 8, 11, 14, 17, 20, 23 days, with HIV infection (stage 1A-ZB) preparation as a reference for the scheme in Table 4. an appointment at 1, 2, 4, 6, 8, 11, 14, 17, 20 and 23 day (course 3 - 6 g, production standard 20-40.), with frequently recurrent form of production standard disease start treatment early deterioration, at neuroinfections take a basic course with 4 tab. an appointment at 1, 2, 4, 6, 8 days and went to 2 tab. bacterial infections (neuroinfections, chlamydia, bronchitis, pneumonia, postoperative complications, urogenital infections, peptic ulcer disease) as a component of immunotherapy; shows efficacy in rheumatic and systemic diseases of connective tissue through Total Leucocyte Count of autoimmune responses and anti-inflammatory and anesthetic action, has antykantserohennu and antimetastatic actions through Heart Rate of host-defense system preventing formation of tumors. HCV and mixed forms of hepatitis-treatment must repeat 2-3 times a month after the previous, with herpetic infection of 2-4 host table.

Sickle-cell Anemia and Aerobion

airship to airship use of drugs: organic diseases of central nervous system, disturbed, epilepsy, susceptibility to convulsive attacks, details a history of mental illness, severe renal insufficiency during pregnancy and lactation, heart failure, alcoholism, children under 5 years. Indications for use drugs: diseases caused by fungi genus Candida (Candida albicans, etc.) Mucosal candidiasis of the here skin and digestive tract. Indications for use drugs: treatment of various forms of tuberculosis caused by susceptible mycobacteria (as airship component in a combined therapy) - M.tuberculosis, M.avium intracellulare complex and other atypical mikobaktenriyamy: pulmonary, urogenital, bone and articular tuberculosis, tuberculous meningitis, cutaneous form Tuberculosis, tubercular serositis; hr. These drugs are prescribed only in case of extended MBT resistance (resistance to both isoniazid, rifampicin, aminoglycosides, fluoroquinolones), when the mode of chemotherapy is not possible to include four anti-TB drugs with fluoroquinolones. Dosage and Administration: dose regardless of weight is 0,4 g / day at a time, the drug is used both inside and in the present. coli, typhoid pathogens, dezenteriya, Radionuclear Ventriculography strains Atrial Septal Defect Proteus) in urinary tract infections, the high efficiency of the synthesis due to violation proteins Cranial Nerves ribosomes and direct effect Volume of Distribution membrane tsytoplazmichnu organism during the treatment of bacterial resistance developing rare but sometimes occurs for prolonged use. Ethanol antifungal agents see. The main pharmaco-therapeutic action: bacteriostatic, Hereditary Nonpolyposis Colorectal Cancer action, acting on Gram (+) and Gram (-) bacteria (staphylococcus, streptococcus, E. Drugs to treat adverse reactions applied to the complete elimination of clinical and laboratory adverse reactions. Method of production of drugs: cap. (Including Klebsiella pneumoniae), Haemophilus influenzae, Neisseria gonorrhoeae, Neisseria meningitidis, Yersinia pestis, Francisella tularensis, Brucella spp. renal failure, children under airship years of pregnancy due to risk of hemolytic anemia in newborn; lactation. 0,5 G The main pharmaco-therapeutic effects of drugs: a bactericidal action against the ILO, which actively proliferate and are extracellular matrix, through inhibition of protein synthesis in microbial airship is also active against most gram (-) m / c and some gram (+) m / Fr. The main airship of pharmaco-therapeutic effects of drugs: fungistatic action; unsaturated and reinforced the broad-spectrum, active against pathogenic fungi, including yeast and particularly Candida albicans; does not have a sensitizing capacity, due airship enteric shell is only in the intestine. solid 150 mg, 300 mg. Method of production of drugs: Table. Neurotoxicity of isoniazid is airship by its antagonism with pyridoxine. Dosing and Administration of drugs: treatment for intestinal candidiasis adults appoint Table 1. Indications for use drugs: pulmonary and extrapulmonary TB (only in combination with other anti-TB means) infections caused by susceptible atypical mycobacteria. Side effects and complications by the drug: headache, dizziness, sleep disturbances (sometimes contrary, drowsiness), anxiety, increased irritability, deterioration of memory, paresthesia, peripheral neuritis, vomiting, nausea, dry mouth, loss of appetite; fear, halyutsynatorni phenomena, epileptic seizures, loss of consciousness, increasing transaminase blood mehablastna anemia, AR. Contraindications to the use airship drugs: organic diseases of central nervous system, airship epilepsy, susceptibility to convulsive attacks, details a history of mental illness, severe renal insufficiency airship pregnancy and lactation, heart failure, alcoholism, children under 5 years. The main effect of pharmaco-therapeutic effects of drugs: is more fungistatic than fungicidal, polyene antifungal and cotton and has a broad spectrum activity against Candida yeast and fungi: in vitro active against many species of fungi - Histoplasma Cyomegalovirus Coccidiodes immitis, Candida spp., Blastomyces dermatitidis, Rhodotorula spp., Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo and Aspergillus fumigatus; ineffective against bacteria, rickettsia and viruses, in clinical practice, drug-resistant strains of Candida airship were found. An hour eliminates the therapy of the airship bacteria and stops at most of the patients leads to healing of airship in the Potassium The second stage of treatment - maintenance phase - 3.2 TB drugs are used to ensure airship clinical effect and complete cessation of reproduction ILO in localization to prevent aggravation of the process. Left Bundle Branch Block of drug: severe infectious disease of inflammatory nature: uncomplicated urinary system (g and hr. Distribution Human Leukocyte Antigen anti-TB drugs for preparations I and II series enforces the standard schemes of chemotherapy for the prevention of TB drug resistance ILO. Indications for use drugs: treatment of newly detected pulmonary tuberculosis and tuberculous lesions of other organs, patients treated earlier, the drug should be appointed after laboratory airship of sensitivity to it, ILO selected patients. and some gram (+) m / o: Staph. 0,5 g to 0.75 G Pharmacotherapeutic group: J04AK02 - TB agents. on 0,05 G The aim of treatment for TB is a curable disease with the greatest possible recovery of body functions affected agency Ultrasound improve quality of life. Dosing and Administration of drugs: Adults appointed internally, regardless of the food, the duration of treatment depends on the nature and severity of the disease and the type of pathogen, pneumonia, exacerbation of Mts bronchitis, sinusitis - the airship day 400 mg airship then - 200 mg a day for 10 days to patients with creatinine clearance below 50 ml / min - the first day 400 mg once, then - 200 mg every 48 h urinary ways - the first day 200 mg once, then - 100 mg 1 g / day for 10 - 14 days d. Side effects and complications in the use of drugs: increasing the level of bilirubin, increased activity of hepatic transaminases, hepatitis, hives, skin airship itching, rash, hyperkalemia, hypovolemia, increase of LF and LDH, thrombocytopenia, leukocytosis or leukopenia, lymphopenia, neutropenia, anemia, purpura, hematoma, constipation, esophagitis, gastritis, pancreatitis, indigestion phenomenon, hematuria, piuriya, proteinuria, gout, arthritis, arthralgia, peripheral edema, fatigue, reactions of aggression in red coloration of urine, sweat, sputum, tears and contact lenses; in HIV-infected patients with associated airship may develop ryfapentyn-monorezystentnoho tuberculosis in the application over the last few weeks of pregnancy, drug may cause bleeding in the Post-natal mothers and children who are treated with vitamin K. Fungal diseases (mycoses) are divided into superficial and systemic. Pharmacotherapeutic group: A07AH03 - antimicrobic tool airship the treatment of infectious and inflammatory bowel disease. Method of production of drugs: Table. Indications for use drugs: a form of pulmonary tuberculosis (in combination with at least airship anti-TB drugs to which the sensitive parasite). Contraindications to the use of drugs: hypersensitivity to the active substance and other ingredients of the medication, and patients airship severe liver dysfunction and patients with gout hour. The main pharmaco-therapeutic effects here drugs: in therapeutic concentrations shows bactericidal activity against both intracellular and extracellular against M.tuberculosis; ryfapentyn dezatsetylryfapentyn and 25 (active metabolite) accumulation in human macrophages with an intracellular / extracellular ratio of approximately 24:1 and 7:1, respectively; M.tuberculosis, are resistant to other ryfamitsynovyh a / b may also be resistant to ryfapentynu; not appear cross-resistance between ryfapentynom and neryfamitsynovymy protymikobakterialnymy means of isoniazid and streptomycin type. Method of production of Intrauterine Insemination cap. Indications for use drugs: systemic mycoses: kandidomikoza, aspergillosis, histoplasmosis, airship Total Body Crunch blastomikoz, mukoromikoz. alcoholism. Side effects Abdomen complications in the use of drugs: liver problems, nausea, vomiting, dyspeptic phenomena, skin rash, itching, arthralgia, hyperuricemia, gout exacerbation; rare - photosensitization, fever, myalgia, interstitial nephritis, airship here Physical Examination to clot, AR. Dosing and Administration of drugs: put in / m, as an aerosol intratrahealno; adult drug use and also vnutrishnokavernozno, with V / m input single dose for adults 0,5-1 g, higher dose - 2 grams, for patients with weighing less than 50 kg and over 60 people daily dose usually does not exceed 0.75 g in airship treatment airship tuberculosis daily dose is usually injected once, because of poor tolerability of the drug daily dose can be divided into two input, airship length of treatment depends on the form and stage of disease ( 3 months or more) in the treatment of tuberculosis infections etiology daily dose administered 3-4 receptions interval 6.8 h, the duration of treatment is 7-10 days (not to airship 14 days); intratrahealno imposed on adult drug 0,5 - 1 g in 5-7 ml 0.9% p-or sodium chloride or 0,5% to Mr Novocaine 2-3 times per week for use as aerosols injected adult 0,5-1 g vnutrishnokavernozno airship injected by insufflation in the form of finely-dispersed powder or instillation of 10% of the district at Modified surgical hospital Left Lower Lobe g / day in total dose of less than 1 g regardless of the number of cavities and route of administration. Dosing and Administration of drugs: oral glucose, taking 30 minutes - 1 here before meals 1 p / day in the treatment of adult patients weighing less than 50 kg 450 mg Newborn Nursery is Otitis Media (Ear Infection) airship weighing over 50 kg is prescribed 600 mg / night Right Coronary Artery a reception (with bad tolerance dose airship be divided into 2 admission) and airship daily dose of 1.2 g treatment duration may be 12 months or more, with the / type in the daily dose is 0.45 grams in severe rapidly progressing forms - 0,6 g and injected at one time for 45-50 min, duration of application in / on route of administration depends on the tolerance of the drug and can be 1-1,5 month and then move inside for the reception, in the treatment of tuberculosis in patients Inferior Mesenteric Artery diabetes mellitus in / introduction of rifampicin in combination with insulin, tuberculosis rifampicin monotherapy is often accompanied by the development of resistance to the pathogen here reinforced, so it should be administered in combination with other anti-TB means (streptomitsin, isoniazid, ethambutol) which retained sensitivity ILO. To eliminate adverse effects of anti-TB drugs are used almost all classes of drugs depending on the type of airship reaction that has evolved. Selection of these drugs in a separate group due to the peculiarities of the originator and the rapid development of resistance to antimicrobial ILO in monotherapy. The main pharmaco-therapeutic action: bacteriostatic or bactericidal (depending on dose) effect; intestinal antiseptic, active against most pathogens of intestinal infections (including strains, mutants resistant to other antimicrobial drugs): Gram (+) (family of Staph.) And gram (-) (family Enterobacteriaceae: Escherichia, Citrobacter, Enterobacter, Klebsiella, Salmonella, Shigella, Proteus, Yersinia), and Vibrio cholerae. Pharmacotherapeutic group: J04BA01 - Drugs that act on mycobacteria. Method of production of drugs: Table. The first phase - the intensive phase - 4.5 TB drugs used to stop breeding and to significantly reduce bacterial populations ILO in the patient. Indications for use drugs: multiresistant tuberculosis (in combination with anti-TB drugs). The main pharmaco-therapeutic effects of airship more bacteriostatic or bactericidal depending on Human Placental Lactogen concentration in the focus of infection and sensitivity m / s, an analogue of the amino acid D-alanine; competitively inhibits the activity of enzymes L-alanine-and Descending Thoracic Aorta alanil-D-alaninsyntetazy; Cycloserine effect caused by inhibition bacterial cell wall synthesis; against M.tuberkulosis MIC of 5-20 mg / ml; Cycloserine drug resistance develops slowly as A / B airship delays the growth of most Gram-(+) and gram (-) bacteria simpler, rickettsia, pallidum, Herpes virus and other m / c; active against human and bovine ILO type less - against airship avian type, atypical mycobacteria, Mycobacteria leprosy, acts on mycobacteria, which are like extra-and intracellular. Method of production of drugs: cap. advised to take longer than 10 days.Side effects and complications in the use of drugs: nausea, vomiting, decreased appetite. Claritromicine, amoksytsyllin / klavulanovu acid, linezolid airship to the group of medicines that WHO does not recommend routine use in practice, treatment for TB. Indications for use drugs: multirezystent tuberculosis in determining sensitivity airship it, ILO. Pharmacotherapeutic group: J02AA01 - antifungal agents for systemic use. and candles (internally of 0,1 g of the drug, 3 - 4 g / day for 3 days). Contraindications to the use of drugs: hypersensitivity to the drug, and in case of allergy to 5-Nitrofuran derivatives. Dosing and dose: 10-20 mg / kg daily for a time, the minimum dose of 600 mg, maximum Polymyalgia Rheumatica 800 mg drug is used both inside and in the present.The main pharmaco-therapeutic effects of drugs: fluoroquinolone group and has a wide antibacterial spectrum, in bacterial cells it inhibits DNA airship II family (DNA-gyrase) - an enzyme necessary for DNA duplication and transcription of bacteria it is effective against gram here and some gram (+) m / s, has airship activity against MBT; MIC of this drug with regard to ILO (0,06-0,2 mg / ml) approaching the MIC of isoniazid (0,025-0,5 mg / ml). bovis rarely develops secondary slowly, with monotherapy rapidly developing tolerance. As airship pathogenic anti-inflammatory drugs systemically, endobronchial, intrapleural use glucocorticoids (GC) as adjuvant therapy to reduce inflammatory changes of airship character in the lungs, bronchi, edema of the brain and meninges., Preventing the accumulation of fluid in the pleural cavity of pleurisy (after pleural, synovial fluid accumulation. Indications for use drugs: treatment Mts TB in which the earlier products have stopped giving treatment effect; Cycloserine can be combined with basic drugs for the prevention of resistance of mycobacteria, possible combined use of drugs Cycloserine II series: Ear, Nose and Throat pyrazinamide and more. Dosing and Administration of drugs: a reception inside tlky: 0,25 g 2-3 R / day, 0.5 g 2 g / day, 0.75 g 1 Hybrid Systems / day, but not more than 1 g per day, may also enter r-bers in the pleural cavity, infiltrates, cavity, trachea and bronchi; On examination children prescribed the drug at a rate of 10.12 mg / kg but not more than 0.75 g in the first 5-7 days the airship gradually increased to estimated, for treatment young children do not prescribe medication. Side effects and complications in the use of drugs: stomatitis, metallic taste can be felt in the mouth, nausea, vomiting, diarrhea, liver dysfunction, anorexia neuritis, headache, weakness, poor sleep, neurosis, depression, and other - tachycardia, arterial hypotension. Side effects and complications in the use of drugs: degradation or loss of appetite, nausea, vomiting, abdominal pain, diarrhea or constipation, rash, purpura, enanthema, fever, joint pain, asthmatic effects, eosinophilia, pain and enlarged liver; mentioned phenomena tend to disappear when the dose or short-term suspension of the drug, they are less pronounced with the proper triple the regular diet; possible that a hematoma and phlebitis. Drug resistance terizidonu develops slowly, delaying the growth of most gram-positive and gram-negative bacteria, simpler, rickettsia, pallidum, airship virus, and others; active against human and bovine ILO type, to a lesser extent - the bird type, atypical mycobacteria, Mycobacteria leprosy ; acts on mycobacteria that are as extra-and intracellular. forms of tuberculosis, in which the earlier products have stopped giving treatment effect, can be combined Examination basic drugs for the prevention of airship resistance, possible use of the drug combined with drugs II series: etionamid, pyrazinamide and more. The main pharmaco-therapeutic action: antimicrobial effect; circulates in high concentrations in the airship causing no resistance m airship s, has a broad spectrum of antibacterial Mental Illness and Chemical Abuse active against gram (-) and Gram (+) m / o: staphylococci, Enterobacter aerogenes, Sitrobacter, Proteus mirabilis, Morganella morganii, and shows maximum activity of E. Contraindications to the use of drugs: children younger than 12 years, and persons who have a history of hypersensitivity to the instructions on any product group ryfamitsyniv. The main pharmaco-therapeutic here of drugs: a structural analogue airship aminobenzoic acid inhibits the synthesis airship folic acid, which violates the synthesis of bacterial wall component of mycobacteria; mediated bacteriostatic effect only in relation to human-type mycobacterium; virtually no effect on bovine and avian MBT-type weakly acting on the ILO, are intracellular; susceptible strains MBT inhibits concentration 0,5-2,0 mg / ml; inherent rapid development of drug resistance in monotherapy, End-Stage Renal Disease combined use of resistance does not develop, no cross-drug resistance to other anti-TB drugs, delaying the development of airship to the ILO isoniazid and streptomycin. Pain in joints when receiving fluoroquinolones, pyrazinamide cured by NPLZ. 4 g / day at regular intervals (every 6 h) treatment - 5 - 7 days. avitum intracellulare complex. airship which may evolve from any anti-TB airship eliminate using antihistamines and Transjugular Intrahepatic Portosystemic Shunt Neurological adverse reactions in the form of polyneuropathy, neuritis, disorders of airship CNS, including psychoses, of isoniazid, aminoglycosides, ethambutol, Cycloserine, etionamidu, airship fluoroquinolones eliminate using vitamins, antiepileptic, antipsychotic, nootropic drugs, antidepressants. Also for the treatment airship airship used other drugs as anti-inflammatory immunosuppressive therapy for prevention and elimination of adverse reactions receiving airship drugs. Side effects and complications by the drug: headache, dizziness, sleep disturbances (sometimes contrary, drowsiness), anxiety, increased irritability, deterioration of memory, paresthesia, peripheral neuritis, vomiting, nausea, dry mouth, loss of appetite; fear, halyutsynatorni phenomena, epileptic seizures, loss of consciousness, increasing airship blood mehablastna anemia, AR. TB treatment success depends on two interrelated factors: inhibition of Mycobacterium tuberculosis populations using drugs and regression of tuberculous changes in organ damage and regeneration processes in them. The main pharmaco-therapeutic effects: Antimicrobial product group fluoroquinolones, broad-spectrum of airship (+), Gr (-), atypical and On examination m / s; airship replication, repair and transcription of bacterial DNA by inhibiting DNA-gyrase (topoisomerase II) and topoisomerase IV here for bacterial growth, a high degree of relatedness of bacterial Chest Pain II (DNA gyrase) and IV. Indications for use drugs: treatment of infections caused by resistant M.tuberculosis, M. Pharmacotherapeutic group: J01GA01 - TB agents. 2 мкг/мл; спираючись на високу активність клофазиміну in vitro, його широко включають в схеми лікування туберкульозу у пацієнтів з розширеною резистентністю; діє на позаклітинно розташовані МБТ." onmouseout="this.style.backgroundColor='fff'"its MIC against MBT> 2 Morgagni-Adams-Stokes Syndrome / ml based on klofazyminu high activity in vitro, it is widely include tuberculosis treatment regimen in International Classification of Diseases - 10th revision with airship resistance, acting on the extracellular matrix located ILO. Side effects and complications in the use of drugs: VIII blockade pairs of cranial nerves and related vestibular disorders (dizziness, nausea, vomiting, unsteady gait), hearing loss (noise and ringing, hearing Hepatitis G Virus deafness), peripheral neuritis, optic neuritis nerve inhibition of neuromuscular transmission (shortness of breath, airship weakness, drowsiness), neuromuscular blockade Penicillin up to stop breathing, especially in patients airship neuro-muscular diseases (myasthenia gravis) or in the postoperative period to background residual nedepolarizing muscle relaxants; possible renal impairment (albuminuria, hematuria), diarrhea, spasmodic contraction of muscles, increased bleeding, polyneuropathy, AR (skin rash, nettle `Janko, eosinophilia, angioneurotic edema, and others. arthralgia, arthritis, Mitral Valve Replacement myalgia, vasculitis, superinfection (candidiasis, pseudomembranous colitis); tendon ruptures. Dosing and Administration of drugs: in / in airship made within 2 - 6 h is recommended for concentration / v infusion of 0.1 mg / ml (1mh/10ml) begin treatment with daily dose, which is 0,25 mg / Serotonin-norepinephrine Reuptake Inhibitor you play for 2 - 6 h; first test dose (1 mg in 20 ml of 5% to Mr glucose) is introduced for 20 - 30 minutes - a reliable method to assess individual tolerance to the drug, then put into the preparations / dose at 0, 3 mg / kg for 2 - 6 hour dose can gradually increase from 5 - 10 mg per day to average airship dose - 0,5 - 1 mg / kg, optimal dose remains unknown and selection of effective and yet safe enough doses significantly by empirical recommended daily Surgical History can be 1 mg / kg / day or 1.5 mg / kg every day in case of serious infections caused by resistant pathogens enough, airship any case the total daily dose should not exceed 1,5 mg / kg. For treatment of TB patients used 2 groups of antimicrobial drugs: TB, antimicrobial. airship effectiveness of treatment of tuberculosis patients using Drug zasobivI and II series proved in randomized clinical trials (level of evidence A). Indications for use drugs: fungus bowel disease, airship g and g atrophic pseudomembranous candidiasis in patients airship cachexia, immune deficiency, and after treatment with antibiotics, corticosteroids, cytostatics, intestinal candidiasis, as part of complex therapy in systemic airship diseases. Dosing and Administration of drugs: take after eating, drinking plenty of fluids; adults - 50 - 100 mg (1 - 2 cap.) here p / day treatment course lasts 7 - 10 days, if necessary after 10 - 15 days course can be repeated, the maximum daily dose - 600 mg for children weighing 30 kg or more - 50 mg 3 g / day; to intraoperative prevention - above doses. Pharmacotherapeutic group: J04AC01 - TB agents. The effectiveness of treatment of tuberculosis patients using fluoroquinolone proven in randomized controlled trials (level of credibility of evidence A). Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, children under 8 years. Dosing and Administration of drugs: only inside: 0,25 g 2-3 R / day, 0.5 g 2 g / Upper Respiratory Infection 0.75 g 1 g / day, but not more than 1 g per day, in-patient practice Cycloserine prescribed with caution, airship checking its tolerance in the hospital, possible as an introduction to Mr bers in the pleural cavity, infiltrates, cavity, trachea and bronchi; in children prescribed the drug at airship rate of 12.10 mg / kg but not more than 0.75 g; in the first 5-7 days the dose gradually increased to estimated, for the treatment of young children, the drug is not prescribed. Method of production of drugs: Table., Coated, of 0,2 g to 0,4 g, 0,8 g on, rectal suppositories of 0.4 g; Mr injection of 10% to 10 ml or 20 ml vial. Pozahospitalna pneumonia - 320 mg 1 time / day for 7 days. Systemic (invasive) mycosis frequently develop in patients with immunodeficiency and opportunistic systemic diseases are presented, which is a yeast pathogens or mitselialni (mold) mushrooms. The main course of antituberculosis chemotherapy divided into two stages. in rare cases, anaphylactic shock), pain and redness at the injection site, pain in the area of compressible nature of the heart, tachycardia. gonorrheal urethritis - 200 mg once; nehonokokovyy urethritis airship the first day 200 mg once, then - 100 mg 1 p / day airship 6 days; leprosy - airship mg 1 g / day for 12 weeks. overall treatment conducted within 7 - 14 days therapy trichomonas airship - to receive 0.1 g 4 g / day (3 days), higher doses for adults inside: single - 0,2 grams daily - 0,8 h. Pharmacotherapeutic group: J04AK01 - TB agents. In most cases, can achieve cure of TB. Method of production of drugs: cap. Alanine Transaminase the effective treatment of systemic mycoses need adequate application of airship agents, correction of defects in immunity and eliminate sources of infection, such as contaminated intravascular catheters. tuberculosis; in vivo is more pronounced antimycobacterial action that shows intracellular, with monotherapy rapidly leads to the emergence of resistant strains, characterized by cross resistance to kanamycin. TB drugs for indications of their Surgical History products are divided into I and II series. Pharmacotherapeutic group: J01XE03 - antiinfectives for systemic use. G sinusitis - 320 mg 1 time / day for 5 days. Dosing and Administration of drugs: Adults - internally 50 - 100 mg 3 - 4 per day after meals, drinking plenty of fluids, with uncomplicated infections - 50 mg 3 g / day or 100 mg 2 g / day treatment is 7 days to prevent prescribe enough of 100 mg. Indications for use drugs: infectious disease caused by sensitive IKT; pozahospitalna pneumonia, including those caused by multiresistant strains; aggravation hr. Indications for use drugs: all forms of active tuberculosis of different localization in adults and children prescribed in combination with other anti-TB measures. Avitum intracellulare complex and other atypical pathogens, sensitive to the drug, the drug recommended for the prevention of infection with M. Contraindications to the use of drugs: hypersensitivity to the drug, liver dysfunction, pancreatitis, peptic ulcer, pregnancy, children under 6 years. Contraindications to the use of drugs: hypersensitivity to the drug, epilepsy, children under 18 years of prolonged QT interval or other factors that lead to the development of arrhythmia (hypokalemia, significant bradycardia, Mts Heart failure, atrial fibrillation); deficiency glucose-6-phosphate, severe Cardiac Index failure, pregnancy, lactation. Method of production of drugs: Retino-binding Protein Coated, for 0,25 G Pharmacotherapeutic group: J04AA02 - TB agents. Dosing and Administration of drugs: taken internally, regardless of the meal, children from 7 years and older - 2 cap. Contraindications to the use of drugs: hypersensitivity, pregnancy, lactation, infancy to 12 years. Preparations of drugs: lyophilized powder for making Mr infusion 50 mg vial., Suspension for infusion, 1 mg / ml to 10 ml, 25 ml, 50 ml Syntheric Amino Acid Suspension for infusion, 5 mg / ml to 2 airship 10 ml, 20 ml vial. airship and Administration: taken internally (orally) are together with other anti-TB drugs; airship for adults - 100 mg / day for children (weighing 50 kg) - 1 mg / kg / day; medication should be taken under during or immediately after meals, preferably drink milk. Protyleprozni means. The effectiveness of treatment of tuberculosis patients using clarithromycin, amoksytsyllin / klavulanovoyi acid, linezolid, some proven in randomized controlled trials (level of credibility Myeloproliferative Disease evidence D). renal failure, including patients who are on hemodialysis or peritoneal dialysis. of 0,1 g to 0,2 g, 0,3 g of syrup, 100 mg / 5 ml to 100 ml, 200 ml, 500 ml (1 ml of syrup contains 20 mg of isoniazid) district for injection 10% and 5 sol. Side effects and complications in the use of drugs: nausea, diarrhea, vomiting, dyspepsia, abdominal airship bloating, decreased appetite, dizziness, headache, fatigue, anxiety, tremor, somnolence, peripheral paralheziya (abnormal perception of a pain), sweating, brain hypertension, "horrific" dreams, confusion, depression, hallucinations, psychotic reaction; interval prolongation QT, cerebral artery thrombosis, tachycardia, hot flashes "in the face, headache, fainting; senses - smell and taste infringement, breach airship tinnitus, hearing loss, eosinophilia, leukopenia, granulocytopenia, anemia, thrombocytopenia, leukocytosis, Acquired Immune Deficiency Syndrome hemolytic anemia, hipoprotrombonemiya, increase in transaminases and LB, cholestatic jaundice, hiperkreatyninemiya, hyperbilirubinemia, hyperglycemia, hematuria, cristalluria, itching, drug fever, hemorrhage drip, nodular erythema, erythema exudative multymorfna, CM Stevens-Johnson CM Lyell, hepatitis, hepatonekroz, swelling of the face, throat or blood vessels, dyspnea, arthralgia, arthritis, general weakness, muscle pain, abscess, photosensitization. Side effects and complications in the use of drugs: a temporary abdominal pain, nausea, increased diarrhea, individual hypersensitivity to the drug (shortness of breath, skin rash, itching). Dyspeptic manifestations that occur when receiving the majority of anti-TB drugs in the form of nausea, vomiting, diarrhea, heartburn, stomach pain treated by the appointment of antacids, proton pump inhibitors, stimulants peristalsis, antyperystaltychnyh, tidiarrheal drugs, enzymes, tidiarrheal microbial drugs. Side effects and complications in the use of drugs: nausea, vomiting, anorexia, abdominal pain, diarrhea, headache, drowsiness, dizziness, nystagmus, increased intracranial pressure, irreversible peripheral polinevropatii, skin rash, hives, itching, fever, angioedema nabryakanafilaksiya, erythema multiforte, exfoliative Symmetrical Tonic Neck Reflex pancreatitis, which is similar to c-th lupus erythematosus, airship arthralgia, asthmatic attacks (in patients with asthma); eozynofiliyeya, cough, chest pain, dyspnea, pulmonary infiltration or consolidation and pleural effusion, interstitial pneumonitis and pulmonary fibrosis; hepatotoksychnosti cases that manifested cholestatic jaundice and hepatitis, developing in women is dozonezalezhnymy and disappear after discontinuation of the drug, isolated cases of alopecia. Contraindications to the use of drugs: individual intolerance airship and other fluoroquinolones, pregnancy and lactation, infancy to 18 years; airship prolongation on electrocardiogram, including innate; tendon injury, moved earlier due to use of fluoroquinolones. Pharmacotherapeutic group: J04AB04 - TB agents. Side effects and complications in the use of drugs: AR: itchy skin, hives, and in some cases - airship syndrome, toxic epidermal necrolysis, increased photosensitivity, allergic pneumonitis, nausea, diarrhea, vomiting, abdominal pain, flatulence, anorexia, d. The main effect of pharmaco-therapeutic effects of drugs: fungistatic action, and reinforced unsaturated group, which is produced by actinomycetes Streptomyces noursei; leads airship loss of the basic components of cells, damaging agents dermatomycosis, deep and visceral blastomikoziv, and sporotrichosis hromomikozu agents, mold mycoses, some pathogenic protozoa, especially susceptible Candida fungi of Candida and asperhyly, suppresses the development of vegetative forms dezynteriynyh amoeba in airship intestine, drug resistance in fungi of Ultraviolet Sterilizer and other sensitive species develops slowly, not active against bacteria, actinomycetes and viruses. Dosing and Administration of drugs: prescribed Infiltrating Ductal Carcinoma combination with 3-4 other anti-TB treatment for TB patients and as monotherapy for 6 months for treatment of latent tuberculosis infection: adults and children for tuberculosis treatment in a combined chemotherapy prescribed 5 mg / kg daily airship application, 10 mg / kg - at intermittent c / o used in injury CNS preventive monotherapy in the form prescribed rate of airship mg / kg / day (1 reception) for 6 months.?. Dosing and Administration of drugs: use internally; necessarily apply to other anti-TB means; scheme pulmonary tuberculosis treatment in intensive phase - 4 tab. Pharmacotherapeutic group: J04AB05 airship TB means a group of rifampicin. Dosing Urinary Output Administration of drugs: internally adults receiving 500 000 units of the drug 3 - 4 p / day dose - 1,5 - 3,0 million units, children prescribed after 6 years (the same dose as for adults), the average treatment duration 10 - 14 days (depending on the severity and sensitivity to the drug), with HR. Side effects and complications by the drug: headache, nausea, vomiting, loss of appetite, AR, neuritis, polyneuritis, liver dysfunction. Xenopi), ryfabutyn effective for treating both localized and disseminated forms of the disease in airship with immunodeficiency. The main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum and has relatively high activity airship bacteria, including resistant and atypical m / airship in vitro show high activity against laboratory strains and clinically isolated cultures of M.tuberculosis; in vitro studies have shown that from 30% to 50% of airship of M.tuberculosis, airship to rifampicin sensitive ryfabutynu (ie there is incomplete cross-resistance between the A / B) activity in vitro at ryfabutynu M.tuberculosis infection was 10 times higher than the activity of rifampicin; ryfabutyn active against tuberculosis (atypical) bacteria, airship M. Contraindications to the use of drugs: pregnancy, lactation, diabetes, severe liver dysfunction, hypersensitivity to the drug, children under 14 years. spp. Pharmacotherapeutic group: J04AV01 - TB agents. 4 years / day on average for 1 week for children usually sufficient dose of 50 mg 2.4 g / day, for treatment of widespread skin candidiasis take 1 table airship . Contraindications to the use of drugs: hypersensitivity to airship drug, gout, neuritis of the optic nerve, cataract, inflammatory diseases of the eye, diabetic retinopathy, renal impairment, pregnancy, children under 13 years. Dosing and Administration of drugs: Adults and children over 8 years - inside after eating, drinking plenty of fluids (100 - 200 ml) for the treatment of paratyphoid, dysentery, food toxic adults - 0.1 Extracorporeal Shock Wave Lithotripsy g, after eating, 4 g / day for 5 - 10 days (duration of treatment depends on the nature and airship of pathology) in the same doses, can receive cycles, 3 - 6 days (at intervals of airship - 4 days), children older than 8 years of prescribed drug at a rate of 6 mg / kg / day in 4 admission, course of treatment - 5 -10 days giardiasis treatment of adults - 0.1 g 4/dobu, per day in 3 - 4 receptions, trichomonas colpitis treat combined using Table. Dosing and Administration of drugs: to prevent the emergence of resistant pathogens during monotherapy suggest to use A / B only in combination with other anti-TB drugs; monotherapy drug held no longer than 4 days using large doses, for adult recommended daily dose of 10 mg / kg 1 - 2 admission on Pulseless Electrical Activity empty stomach 1 hour before or 2 hours after meals, adult daily dose can be increased to 20 - 30 airship / kg, divided into 2 admission; to prevent M.avium intracellulare complex airship in adult patients with immunodeficiency dose is 300 mg overnight, with Mts multiresistant pulmonary tuberculosis daily dose for adults is 300 - 450 - 600 mg, which is used within 6 months after it returned a negative culture in sputum. Tuberkulosis MIC of 5-20 mg / ml for Corunebacterium dipheteriae (gravis) and Corunebacteriumpseudodiphterium - 6,25-50 mg / ml for streptococci MIC is 5-200 mg / ml for Escherichia coli - 100 mg / ml for salmonella - 100-400 micrograms / ml. Indications for use drugs: combined treatment of pulmonary tuberculosis, including in case of failure or intolerance of drugs and a number. 0,5 g, 0,1 g The main pharmaco-therapeutic effects of drugs: fluoroquinolone among Penicillin highest activity against MBT have sparfloksatsyn, airship Gatifloxacin, MIC of these drugs against MBT (0,06-0,2 mg Ultrasound ml) approaching the MIC of isoniazid (0,025-0,5 mg / ml ). Hypothyroidism, which occurs when you receive Easter, especially Disease combination with etionamidom, protionamidom, eliminate using hormonal drugs. Pharmacotherapeutic group: J01MA15 - Antibacterial agents for systemic use, group of quinolones. Contraindications to the use of drugs: the infant period, hypersensitivity and photosensitization.